Abstract

Introduction: Stereotactic biopsy for deep-seated intracranial lesions is a minimally invasive method preferred for diagnosis in surgically inaccessible or high-risk areas. In this study, diagnostic accuracy, safety and clinical outcomes of stereotactic biopsies performed between 2012 and 2024 were evaluated.

Methods: We retrospectively analysed 70 patients who underwent stereotactic biopsy between 2012 and 2024 at Ondokuz Mayıs University. Demographic characteristics, presenting symptoms, lesion localisation, pathological diagnoses and length of stay of 59 patients who met the exclusion criteria were analysed.

Results: The mean age of the patients was 53.8 years and lesions were most commonly located in the thalamus (35.6%) and basal ganglia (22%). Pathological diagnosis was obtained in 74.6% of the biopsies. The most common diagnoses were high-grade glial tumour (49.2%) and lymphoma (16.9%). There was no significant correlation between the localisation of the lesion and the presenting symptoms and pathological results (p>0.05). There was a significant difference between the pathological diagnosis and the length of hospitalisation; the length of hospitalisation was significantly longer in patients with lymphoma and infection (p=0.003). No serious postoperative complications were observed.

Conclusion: Stereotactic biopsy is a safe, effective and highly diagnostic method for deep-seated brain lesions. The pathological diagnoses obtained contribute to treatment planning, especially in the differentiation of glioma, lymphoma and infection. The findings show that this method is an important tool in clinical decision-making processes by providing accurate diagnosis with minimal risk.

Keywords: sterotactic biopsy, deep-seated brain tumour, minimally invasive surgery

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Copyright and license

Copyright © 2025 The Author(s). This is an open access article distributed under the Creative Commons Attribution License (CC BY), which permits unrestricted use, distribution, and reproduction in any medium or format, provided the original work is properly cited.

How to cite

1.
Engin R, Karatoprak DE, Özen AC, Şener H, Durmuş YE, Baydın ŞS. Sterotactic biopsy in deep-seated brain lesions: A retrospective evaluation of diagnostic efficacy and clinical results. Sinir Sistemi Cerrahisi Derg 2025;10(1):1-9. https://doi.org/10.54306/sscd.2025.216