Systemic diseases accompanying osteoporosis in postmenopausal patients undergoing percutaneous vertebroplasty




Postmenopausal, vertebroplasty, osteoporosis


Objective: Vertebroplasty was first performed in 1984 in a patient with vertebral hemangioma. As the average life expectancy increased, the rates of osteoporosis increased, and as a result, the incidence of compression fractures increased. It is a minimally invasive technique involving the injection of polymethylmethacrylate (PMMA) from the pedicles to the vertebral body. In this study, comorbidities and the frequency of these diseases were evaluated in postmenopausal osteoporosis (PMO) patients with vertebral compression fracture (VCF) who underwent percutaneous vertebroplasty (PVP).

Materials and Methods: 69 female patients with PMO who underwent PVP for VCC between May 2015 and May 2019 in our neurosurgery clinic were retrospectively reviewed. The accompanying systemic diseases along with the demographic data of the patients were recorded from the patient files.

Results: The mean age of the patients included in our study was 73.30 ± 9.09 (49-92 years) years. Hypertension, It ranked first among the accompanying systemic diseases with a rate of 39.1%. Then in descending order osteoarthritis (OA), type II diabetes mellitus (DM), gastrointestinal system diseases, cardiac diseases, cerebrovascular diseases, Alzheimer’s disease, chronic obstructive pulmonary disease (COPD), previous spinal surgery, thyroid diseases, anemia, chronic renal failure (CRF), epilepsy, smoking, glaucoma, malignancy and depression were detected. The number of patients with no features in their history was 13%.

Conclusion: The severity of PMO, which is common in our country and all over the world, especially in the elderly population, may increase with systemic diseases and some surgical interventions, or its treatment may be impaired. Prevention from osteoporosis and accompanying systemic diseases is more important than surgical intervention.


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How to Cite

Özger Özkan, Kaplan N. Systemic diseases accompanying osteoporosis in postmenopausal patients undergoing percutaneous vertebroplasty. J Nervous Sys Surgery [Internet]. 2021 Aug. 31 [cited 2022 Aug. 15];7(2):72-7. Available from:



Research Article