Konveksite Meningiomunu Taklit Eden Kafaiçi Plazmositom ile Bulgu Veren Nüks Multipl Miyelom [Sinir Sistemi Cerrahisi Dergisi]
Sinir Sistemi Cerrahisi Dergisi. 2008; 1(3): 173-175

Konveksite Meningiomunu Taklit Eden Kafaiçi Plazmositom ile Bulgu Veren Nüks Multipl Miyelom

Haldun Şükrü Erkal1, Emin Kaya2, Çağatay Önal3, İclal Gürses4

Altmış yedi yaşında bayan hasta bir haftadır artan belirgin başağrısı ve kusma öyküsü ile acilen başvurdu. Bir yıl önce multipl miyelom tanısı mevcut olup ilk basamak kemoterapi uygulanmıştı. Fizik muayenede belirgin sol hemiparezi belirlendi. Beyin manyetik rezonans görüntülemesinde meninkslerden köken alan ve belirgin çevresel ödem oluşturarak orta hat yapılarını sola iten sağ hemisferde kitle lezyonu saptandı. İhtimali konveksite meningiomu ön tanısı ile hastaya acil kranyotomi ve kitle eksizyonu uygulandı. Tanı kafaiçi plazmositom olarak belirlendi. İleri tedavi radyoterapi ile sürdürüldü. Mevcut bulgularla olgu nüks multipl miyelom tanısı alarak ikinci basamak kemoterapiye geçildi. Cerrahi girişimden bir yıl sonraki takip muayenesinde hasta salimdi.



Relapsed multiple myeloma presenting with an intracranial plasmacytoma mimicking a convexity meningioma

Haldun Şükrü Erkal1, Emin Kaya2, Çağatay Önal3, İclal Gürses4
1Department Of Radiation Oncology, İnönü University Faculty of Medicine, Malatya, Turkey
2Department of Hematology, İnönü University Faculty of Medicine, Malatya, Turkey
3Department of Neurosurgery, İnönü University Faculty of Medicine, Malatya, Turkey
4Department of Pathology, İnönü University Faculty of Medicine, Malatya, Turkey

A 67 year-old woman presented with pronounced headache and vomiting that had progressed over one week. One year ago, she had been diagnosed as having multiple myeloma and had been treated with first-line chemotherapy. Her physical examination revealed marked left-sided hemiparesis. On magnetic resonance imaging of the brain, a right-sided mass lesion that appeared to originate from the meninges was associated with intense oedema that resulted in left-sided shift of the midline structures. The presumptive diagnosis of a convexity meningioma was made. The patient underwent an emergency craniotomy with resection of the mass lesion and was diagnosed as having an intracranial plasmacytoma. The decision was made to proceed with radiation therapy. In the interim, the patient was diagnosed as having relapsed multiple myeloma and was treated with second-line chemotherapy accordingly. She was alive at the follow-up visit one year following surgery.

Keywords: Multiple myeloma, intracranial plasmacytoma, convexity meningioma, surgery, radiation therapy, chemotherapy


Haldun Şükrü Erkal, Emin Kaya, Çağatay Önal, İclal Gürses. Relapsed multiple myeloma presenting with an intracranial plasmacytoma mimicking a convexity meningioma. Sinir Sistemi Cerrahisi Dergisi. 2008; 1(3): 173-175

Sorumlu Yazar: Çağatay Önal, Türkiye


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